• Document: USMLE * Step 1. medical. Pharmacology Notes KAPLAN"
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* USMLE Step 1 Pharmacology Notes KAPLAN" medical *USMLE is a j o i n t program of t h e Federation of State Medical Boards of the Unted States. Inc. and the National Board of Medical Examiners. 02002 Kaplan, Inc. All rights reserved. No part of this book may be reproduced in any form, by photostat, microfilm, xerography or any other means, or incorporated into any information retrieval system, electronic or mechanical, without the written permission of Kaplan, Inc. Executive Editor and Contributing Author Anthony Trevor, Ph.D. Professor Emeritus Department of Cellular and Molecular Pharmacology University of California San Francisco, C A Contributing Authors Executive Director of Curriculum Maris Victor Nora, Pharm.D., Ph.D. Richard Friedland, M.D. Associate Professor Rush Medical College Director of Publishing and Media Chicago, IL Michelle Covello Lionel P. Raymon, Pharm.D., Ph.D. Director of Medical Illustration Department of Pathology Christine Schaar Forensic Toxicology Laboratory University of Miami School of Medicine Managing Editor Miami, FL Kathlyn McGreevy Craig Davis, Ph.D. Associate Professor Production Editor University of South Carolina School of Medicine Ruthie Nussbaum Department of Pharmacology and Physiology Columbia, SC Production Artist Michael Wolff Contributor Kenneth H. Ibsen, Ph.D. Cover Design Director of Academic Development Joanna Myllo Kaplan Medical Professor Emeritus Biochemistry Cover Art University of California-Irvine Christine Schaar Irvine, C A Table of Contents Preface . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . vii Section I: General Principles Chapter 1: Pharmacokinetics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 3 Chapter 2: Pharmacodynamics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 19 Section 11: Autonomic Pharmacology Chapter I:The Autonomic Nervous System (ANS) . . . . . . . . . . . . . . . . . . . . 39 Chapter 2: Cholinergic Pharmacology . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 45 Chapter 3: Adrenergic Neuroeffector Junctions . . . . . . . . . . . . . . . . . . . . . . . 53 Chapter 4: Autonomic Drugs: The Eye and Cardiovascular System . . . . . . . . 63 Chapter 5: Autonomic Drug Summary . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 71 Section Ill: Cardiac and Renal Pharmacology Chapter 1: Fundamental Concepts . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 85 Chapter 2: Antiarrhythmic Drugs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 91 Chapter 3: Antihypertensive Drugs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 95 Chapter 4: Drugs for Heart Failure . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 103 Chapter 5: Antianginal Drugs . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 109 Chapter 6: Diuretics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 115 Chapter 7: Antihyperlipidemics . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . . 123 KAPLAN'

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